holdase

noun

Etymology

From hold + -ase?

  1. derived from *kel-
  2. derived from *haldaną
  3. derived from *haldan
  4. derived from healdan
  5. derived from holden
  6. suffixed as holdase — “hold + ase

Definitions

  1. A particular kind of molecular chaperone that assists the non-covalent folding of…

    A particular kind of molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner. Holdases bind to protein folding intermediates to prevent their aggregation but without directly refolding them.

    • As a part of that network, holdase chaperones are able to communicate with other chaperones in the network, to achieve refolding of misfolded clients.

The neighborhood

Vish — recursive loop

No curated loop yet for holdase. Loops are being traced one word at a time while the ingestion pipeline matures.

sense glosses and etymology drawn from English Wiktionary · source · CC-BY-SA